Depressant isn’t linked to depression tho. Get that idea out of your head completely. Like seriously go read some neuro textbooks and stop getting your pharmacology info from tiktok. Depressants depress the CNS… depression is a mental illness.
Also I’ve abused psychs and known a few others that did and I wouldn’t call any of our our activities/side effects manic or psychotic by any means. I know one person who had a family history of schizophrenia that had negative effects like that from their abuse. But just the one. I’d be interested in scholarly articles about the subject tho since I have biased data, and apparently, yours is not, at least from what one would construe from your comment.
There’s a Wikipedia article on US interventions but it misses some afaik.